The TRUPCR® Carbapenem Resistance Detection Kit is an in vitro nucleic acid amplification assay for the qualitative detection and differentiation of blaKPC, blaNDM, blaVIM, blaOXA-48-like, and blaIMP gene sequences associated with carbapenem non-susceptibility using Real-Time PCR. This kit is intended for the rapid detection of the most clinically relevant carbapenem resistance genes. The results must be interpreted within the context of all relevant clinical and laboratory findings.
Each reaction includes an endogenous reference control to monitor PCR performance and detect inhibition.
Key Features:
- Research Use Only (RUO)
- Reliable detection and differentiation of key carbapenemase resistance genes (blaKPC, blaNDM, blaVIM, blaOXA-48-like, blaIMP)
- Based on multiplex TaqMan® probe chemistry for high specificity
- Includes all reagents and positive/negative controls for the assay
- Limit of detection (LoD) as low as 10²–10³ CFU/ml, depending on target gene
- High sensitivity and specificity validated with clinical samples (Sensitivity: 98.25%, Specificity: 98.81%)
- Compatible with multiple Real-Time PCR instruments:
- Applied Biosystems™ 7500 / 7500 Fast Dx
- Applied Biosystems™ QuantStudio® 3 & 5
- Rotor-Gene Q
- Bio-Rad CFX96
- Easy-to-use, rapid, and reliable workflow
