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TRUPCR® ALL PCR Panel Kit

The TRUPCR® ALL PCR panel is intended for the qualitative detection of diagnostic and prognostic markers of acute lymphoblastic leukaemia (ALL) in peripheral blood samples using Real-time PCR.  The TRUPCR® ALL PCR Panel kit is a comprehensive kit which includes complete cDNA chemistry for RNA based transcripts.

Key Features:

  • TRUPCR® ALL PCR Panel allows comprehensive detection of most common diagnostic and prognostic markers for ALL.
  • It detects most common variants of transcripts in the fusion genes.
  • The kit offers sensitivity to detect up to 10 copies of fusion transcripts.
  • All the reagents for cDNA chemistry, PCR and Real-time PCR are included in the kit.
  • It is compatible with various Real-time & Conventional PCR instruments.
  • Easy-to-use, rapid, reliable, comprehensive and cost-effective tests.

Mutation Variants detected by TRUPCR® ALL Panel Kit

No. GENE VARIENT
1 BCR-ABL1 e13a2 & e14a2 (p210)
e1a2 (p190)
e19a2 (p230)
2 TEL-AML1 BCL2L14-RUNX1
3 E2A-PBX1 TCF3-PBX1
4 MLL-AF4 MLL_AF4_e10-e4
MLL_AF4_e9-e4
MLL_AF4_e9-e5
MLL_AF4_e11-e4
MLL_AF4-e9-e6
5 MLL-AF9 MLL-AF9 _e8-e9
MLL-AF9 _e8-e10
MLL-AF9 _e10-e6
6 MLL-ENL MLL-ENL_e9-e2
MLL-ENL_e10-e2
7 ABL1 Control

Acute lymphoblastic leukaemia (ALL) is mainly a disease of childhood that arises from recurrent genetic alterations that block precursor B- and T-cell differentiation and drive aberrant cell proliferation and survival. Due to the advances in the cytogenetic and molecular characterization of the acute leukaemias in the past two decades, genetic alterations can now be identified in more than 80% of cases of ALL. These genetic lesions influence the prognosis and therapeutic approach used for treatment of ALLs. Chromosomal translocation is the hallmark of leukaemias and acute lymphoblastic leukaemia (ALL) in particular. DNA damage arises from endogenous and exogenous genotoxic factors and lack of complete fidelity in DNA-repair leads to chromosomal translocations. Chromosomal breakpoints tend to occur at transcriptionally active DNA sites and the fusion gene transcripts generally involve genes which frequently encode cell cycle regulators, transcription factors, signal transduction molecules, receptors or immunoglobulin and TCR molecules. Due to the chromosomal translocations and subsequent expression of fusion gene transcripts, the normal functions of the genes are altered.

Ordering Information:

CAT. NO. PRODUCT CONTENTS
3B1405 TRUPCR® ALL Panel Kit 24 Reactions
3B1408 TRUPCR® ALL Panel Kit 48 Reactions
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With an experienced team and innovative products, TRUPCR Europe supplies high quality qPCR molecular diagnostic products throughout Europe.

We offer technical support and training on all our products and are committed to increasing the efficiency of laboratory testing and enhancing patient care.

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  • Home
  • Products
    • Oncology & Haematology
      • Individual Markers
        • C-KIT Mutation Detection Kit
        • CALR Kit
        • FLT3 Mutation Detection Kit
        • NPM1 Qualitative KIT
        • NPM1 Mutation Quantitative Kit
        • JAK2 KIT
        • JAK-2 Allele Burden Kit
        • PML-RARA Quantitative
        • PML-RARA Qualitative (BCR1, BCR2, BCR3)
      • Individual Markers BCR-ABL1
        • BCR-ABL1 b2a2/b3a2 Differentiation Kit
        • BCR-ABL Quantitative Kit
        • BCR ABL Qualitative Kit
        • BCR-ABL1 Transcript Screening Kit
      • Solid Tumours Individual Markers
        • EGFR Real-time PCR Kit
        • KRAS Real-time PCR Kit
        • MGMT Methylation Detection Kit
        • BRAF Mutation Kit
        • NRAS Mutation Kit
        • ROS1 Fusions Detection Kit
      • Panel Kits
        • ALL PCR Panel Kit
        • AML Panel Kit
        • MPN Panel Kit
        • Paediatric Leukemia Panel Kit
    • Extraction
      • Silica extraction
        • Blood DNA Extraction Kit
        • Blood RNA Extraction Kit
        • Total Viral Nucleic Acid Extraction Kit
        • Viral RNA Extraction Kit
        • MTB DNA Extraction Kit
        • Total Viral Nucleic Acid Extraction Kit
        • Tissue DNA Extraction Kit
    • Infectious Disease
      • Panel Kits
        • Influenza Panel Kit
        • Flu Panel with RSV detection Kit
        • NAAT Kit
        • Neuro Panel Kit
        • STD Panel Kit
        • Respiratory Pathogen Panel Kit
        • TORCH Panel Kit
        • Tropical Fever Panel Kit
        • UTI ID Panel Kit
      • Individual Markers: STI
        • CMV QT Kit
        • CT/NG Real-Time PCR Detection Kit
        • EBV Virus Detection Kit
        • HBV Viral Load PCR Kit
        • HCV Viral Load Kit
        • HIV Viral Load Kit
        • HCV Genotyping Kit
        • HIV 1/2 Detection Kit
        • HSV Real-time PCR Detection Kit
        • HPV High Risk (E6/E7) Kit
        • HPV 16 & 18 Kit
      • Bacterial Diseases
        • MTB Kit (Nested single step real-time PCR)
        • One Step nested Kit (MTBC and NTM)
        • Leptospira Detection Kit
      • Parasitic Diseases
        • Toxoplasma Detection Kit
      • Viral Diseases
        • BKV Viral Load Kit
        • SARS-CoV-2 RT-qPCR Kit
        • H1N1 (Swine Flu) Detection PCR Kit
      • Vector Borne Diseases
        • Zika Virus Detection Kit
        • Chikungunya Detection Kit
        • Dengue Detection kit
        • Dengue / Chikungunya PCR Kit
        • Malaria Detection Kit
    • Human Genetics
      • Human Genetics
        • Factor II Prothrombin Mutation (G20210A) Detection Kit
        • Factor V Leiden Mutation (G1691A) Detection Kit
        • MTHFR Mutation Kit
        • Coagulation/ Thrombophilia Panel qPCR Kit
        • HLA B27 PCR Kit
    • Antimicrobial Resistance
      • Panel Kits
        • UTI AST Panel Kit
      • Individual Markers
        • MRSA Detection Kit
        • Rif/INH MTB Drug Resistant Detection Kit
        • Rifampicin Resistant MTB Kit
  • Careers
  • Events
  • News
  • About us
  • Contact
TRUPCR Europe