The TRUPCR® NUP214 (CAN) Rearrangements Kit is a real-time PCR–based assay designed for the qualitative detection of NUP214 (CAN) gene rearrangements, specifically DEK-CAN and SET-CAN fusion transcripts, in peripheral blood or bone marrow samples. These rearrangements are recurrent but clinically significant events in acute leukemias.
Key Features:
- RUO (Research Use Only)
- Targeted Detection: Qualitative identification of DEK-CAN (e9–e18) and SET-CAN (e7–e18) fusion transcripts.
- High Sensitivity: Analytical sensitivity with a limit of detection of 10 copies per reaction.
- Endogenous Control Included: ABL1 internal control ensures RNA quality and assay validity.
- All inclusive kit: The Assay includes all the PCR components including PCR Pre-mix / mastermix for optimized results.
- Platform agnostic: Easy work flow & compatible with various Real Time PCR instruments
