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TRUPCR® ROS1 Fusions Detection Kit

Test Overview

The TRUPCR® ROS1 Gene Fusions Detection Kit is intended for the qualitative detection of 14 ROS1 gene fusions in human NSCLC formalin-fixed paraffin- embedded (FFPE) tissue samples using real time PCR system. The human ABL1 gene serves as an internal control for human nucleic acid, also included in this kit.

Principle and Procedure

It has two-step protocol in which total RNA is reverse- transcribed, and the generated cDNA is amplified by PCR using a pair of specific primers and a specific internal double-dye probe of ROS1 and endogenous control gene ABL1 to monitor the quality and quantity of extracted RNA.

Tube.No. ROS1 Spliced Exon Spliced Gene & Exon Remarks
1 ROS1 exon32

SLC34A2 exon4 & & SLC34A2 exon14del

CD74 exon6

SDC4 exon2

SDC4 exon4

It detects 5 fusions but does not distinguish between them.
2 ROS1 exon34

SLC34A2 exon4 & SLC34A2 exon14del

CD74 exon6

SDC4 exon4

EZR exon10

It detects 5 fusions but does not distinguish between them.
3 ROS1 exon35

TPM3 exon8

LRIG3 exon16

GOPC exon8

It detects 3 fusions but does not distinguish between them.
4 ROS1 exon36 GOPC exon4 It detects 1 fusion.

Key Features

  • Detection of 14 ROS1 fusion gene transcripts in single test.
  • One step kit for fast (~ 80 min) screening of ROS1 status of patient.
  • All inclusive kit: The Assay includes cDNA preparation components and all the PCR components including PCR Pre-mix / mastermix for optimized results.

Ordering Information:

CAT. NO. PRODUCT CONTENTS
3B1259 TRUPCR® PML/RARA Quantitative Kit 24 Reactions
3B1260 TRUPCR® PML/RARA Quantitative Kit 48 Reactions
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With an experienced team and innovative products, TRUPCR Europe supplies high quality qPCR molecular diagnostic products throughout Europe.

We offer technical support and training on all our products and are committed to increasing the efficiency of laboratory testing and enhancing patient care.

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Manchester M15 6SE

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  • Home
  • Products
    • Oncology & Haematology
      • Individual Markers
        • C-KIT Mutation Detection Kit
        • CALR Kit
        • FLT3 Mutation Detection Kit
        • NPM1 Qualitative KIT
        • NPM1 Mutation Quantitative Kit
        • JAK2 KIT
        • JAK-2 Allele Burden Kit
        • PML-RARA Quantitative
        • PML-RARA Qualitative (BCR1, BCR2, BCR3)
      • Individual Markers BCR-ABL1
        • BCR-ABL1 b2a2/b3a2 Differentiation Kit
        • BCR-ABL Quantitative Kit
        • BCR ABL Qualitative Kit
        • BCR-ABL1 Transcript Screening Kit
      • Solid Tumours Individual Markers
        • EGFR Real-time PCR Kit
        • KRAS Real-time PCR Kit
        • MGMT Methylation Detection Kit
        • BRAF Mutation Kit
        • NRAS Mutation Kit
        • ROS1 Fusions Detection Kit
      • Panel Kits
        • ALL PCR Panel Kit
        • AML Panel Kit
        • MPN Panel Kit
        • Paediatric Leukemia Panel Kit
    • Extraction
      • Silica extraction
        • Blood DNA Extraction Kit
        • Blood RNA Extraction Kit
        • Total Viral Nucleic Acid Extraction Kit
        • Viral RNA Extraction Kit
        • MTB DNA Extraction Kit
        • Total Viral Nucleic Acid Extraction Kit
        • Tissue DNA Extraction Kit
    • Infectious Disease
      • Panel Kits
        • Influenza Panel Kit
        • Flu Panel with RSV detection Kit
        • NAAT Kit
        • Neuro Panel Kit
        • STD Panel Kit
        • Respiratory Pathogen Panel Kit
        • TORCH Panel Kit
        • Tropical Fever Panel Kit
        • UTI ID Panel Kit
      • Individual Markers: STI
        • CMV QT Kit
        • CT/NG Real-Time PCR Detection Kit
        • EBV Virus Detection Kit
        • HBV Viral Load PCR Kit
        • HCV Viral Load Kit
        • HIV Viral Load Kit
        • HCV Genotyping Kit
        • HIV 1/2 Detection Kit
        • HSV Real-time PCR Detection Kit
        • HPV High Risk (E6/E7) Kit
        • HPV 16 & 18 Kit
      • Bacterial Diseases
        • MTB Kit (Nested single step real-time PCR)
        • One Step nested Kit (MTBC and NTM)
        • Leptospira Detection Kit
      • Parasitic Diseases
        • Toxoplasma Detection Kit
      • Viral Diseases
        • BKV Viral Load Kit
        • SARS-CoV-2 RT-qPCR Kit
        • H1N1 (Swine Flu) Detection PCR Kit
      • Vector Borne Diseases
        • Zika Virus Detection Kit
        • Chikungunya Detection Kit
        • Dengue Detection kit
        • Dengue / Chikungunya PCR Kit
        • Malaria Detection Kit
    • Human Genetics
      • Human Genetics
        • Factor II Prothrombin Mutation (G20210A) Detection Kit
        • Factor V Leiden Mutation (G1691A) Detection Kit
        • MTHFR Mutation Kit
        • Coagulation/ Thrombophilia Panel qPCR Kit
        • HLA B27 PCR Kit
    • Antimicrobial Resistance
      • Panel Kits
        • UTI AST Panel Kit
      • Individual Markers
        • MRSA Detection Kit
        • Rif/INH MTB Drug Resistant Detection Kit
        • Rifampicin Resistant MTB Kit
  • Careers
  • Events
  • News
  • About us
  • Contact
TRUPCR Europe